Questions tagged [microfluidics]

For questions which are in the context of microfluidics. Microfluidics is a multidisciplinary field intersecting engineering, physics, chemistry, biochemistry, nanotechnology, and biotechnology, with practical applications to the design of systems in which small volumes of fluids will be handled. This is typically the sub-milimeter scale.

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3answers
81 views

How do you imagine momentum?

If you want to explain it to a layman (who belongs to the science stream ofc!!) how do you explain it? Also, what is momentum transfer when it comes to fluid mechanics?
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1answer
38 views

CFD simulation of an Air and Oxygen gas gradient in a microfluidics device

I am in the process of manufacturing a microfluidic device for use in research, and would like to do a CFD simulation of the interior of the device to see if an oxygen gradient is formed. The idea is ...
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How does a microfluidic lipid nanoprecipitate mixer for mRNA vaccine production look like and operate?

Apparently, in the production of mRNA vaccines the microfluidic components play a major part in encapsulating the mRNA in a stable lipid coat (the technical term is likely not 'coat'). This step is ...
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1answer
46 views

How can I confirm nL Volume Measurement for Pump and Sensor Calibration

I'm dispensing around 1uL of volume with 1% accuracy. Although I'm confident in my pump, I'd like to be able to routinely confirm that I'm getting the exact volume I'm requesting every time. How can ...
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2answers
43 views

Pushing fluid through microfluidics

my team is working on a project where fluid (mostly water) need to be pushed through small channels (like small pipes) in order to reach larger reservoir. We were considering using air to push the ...
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2answers
334 views

Weight Sensing Problem: Need to detect 10kg load down to milligram accuracy

So I need to build some type of scale where one can place four 600mL beakers on it and measure out its weight down to a milligram level of accuracy. I'm doing this so I can dose a very small amount of ...
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1answer
645 views

How to calculate flow rate of viscous fluids through a funnel-shaped needle?

How would you determine the flow rate of a liquid that flows through a narrow microneedle channel and then through the opening of a funnel, i.e. pouring liquid through the other end of a funnel? I'...
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1answer
44 views

Reusable 100um x 5mm flow chamber

I'm building a small microscope through which I need to pump fluid samples to image. Currently I'm using a flow chamber from Ibidi that is perfect (length of a standard microscope slide x 5mm x 0.1mm)...
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1answer
104 views

Are there basic rules to properly design vein channels?

I am trying to model a prototype resembling a section of vein channels. I am wondering if there are some basic rules for such fluid channels, for instance when a vein splits in two capillaries, is ...
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2answers
162 views

Shear rate of a fluid in a container with a sliding PTFE top plate. Will the liquid move with the plate?

I am trying to work out how a liquid inside a container will be affected by the back and forth sliding of a Teflon coated plate such as the one in the picture. I know how to work out the shear rate ...
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1answer
136 views

What's the smallest pin-like hole I can machine into a piece of tungsten using a metal lathe and common carbide tools?

I am going to machine something out of a small 40mm long x 8mm diam tungsten rod. The majority will be hollowed out using a larger bit, but at the very tip, I need a small hole, the smaller the ...
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4answers
784 views

Precision measurement of liquid levels

How can I measure changes in liquid level of the order of 50 μm? The tank is cylindrical with a radius of about 12.5 mm and a total volume of about 45 ml. The fluid is water-based. The technique ...
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2answers
268 views

Ensuring even flow in liquid pumping in distribution circuit under suction

I have a liquid circuit which looks a bit like that: The system is under suction, and the flow rate through each unit should be about 10ml/min. However, we noticed that unit ...
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2answers
2k views

Can you use the Hagen-Poiseuille equation for a pipe which radius is in the sub-millimeter region?

As this will depend on Pressure drop $\Delta p$, assume that it does not leave the range from 0 to 100 bar. The Hagen-Poiseuille equation for an incompressible fluid is defined as: $$ \dot{V} = \frac{...