there are several reasons.
Fire hazard: A space as large as these big box floor areas have to be divided into smaller fire skirts on the ceiling to contain the spread of a potential fire. If you look up to the ceiling you will see it is being partitioned by either corrugated sheets or some other noncombustible material hanging from the ceiling into a square pattern of parapets.
Storage space of the merchandise stacked up and enough height for the lift trucks to easily move them up and down. The storage is right above the merchandise.
Architectural considerations. A short very large space ceiling is not flattering at all, would not have a pleasant scale, and look welcoming, worse when it is cluttered with suspended signs.
Acoustics, It will be Reflectreflect and amplify the noises.